Abstract

Our physical and cyber environments are becoming increasingly intertwined with smarter sensing, communication, and data analytics. Our daily livings are indeed surrounded by a wide variety of sensors, IoT connectivity, and edge computing devices, constituting smart grid, smart city, smart transportation, and so on. The availability of sensing devices with measurement, communication, and processing capabilities is providing fine-grained data. Together with multimodal sensory data collection and sensor fusion can result in actionable insights and decisions. This synergy can lead to improved ways and quality of life in what we call smart living. 

Magnetism is one of the six energy forms of measurands in sensing. Magnetic sensing plays a critical role in smart living due to various sources of magnetic fields such as magnetic fields from current-carrying wires and permanent magnets which are geometrically determined by Biot-Savart Law and Ampere's Law respectively. These magnetic fields can range from DC to AC, from low frequency to high frequency. Modern civilization heavily relies on electricity which are generated, transmitted, and utilized through various kinds of transmission medium and electrical machines that are composed of current-carrying conductors, electromagnets, and permanent magnets. As such, magnetic field sensing is an important source of data and thus information for condition monitoring of power generation, transmission, and distribution.   

In this talk, we will discuss the various opportunities and alternatives magnetic field sensing can offer in condition monitoring and anomaly detection in smart grid and smart city. Since it is contactless sensing, its installation is easy and it can be easily retrofitted to the existing plant and equipment. This will minimize cost, avoid wear and tear, and meet stringent reliability requirement. Contactless magnetic sensing can complement the traditional contact measurement techniques and help to overcome the major obstacle towards pervasive sensing due to its scalability

Biography

Philip W. T. Pong received a B.Eng. from the University of Hong Kong (HKU) in 2002 with 1st class honours. Then he obtained a PhD in engineering at the University of Cambridge in 2005. He was a postdoctoral researcher at the Magnetic Materials Group at the National Institute of Standards and Technology (NIST) for three years. Currently he is an Associate Professor in the Department of Electrical and Computer Engineering at New Jersey Institute of Technology (NJIT).His research interest focuses on the fault detection, predictive maintenance, and anomaly detection of power grid. He is the Founding Director of the Green Technology Research and Training Laboratory, leading the research and education activities of offshore wind energy at NJIT. Philip Pong is a Fellow of the Institution of Engineering and Technology (FIET), a Fellow of the Institute of Physics (FInstP), a Fellow of the Energy Institute (FEI), a Fellow of the Institute of Materials, Minerals and Mining (FIMMM), a Fellow of the Hong Kong Institution of Engineers (FHKIE), a Fellow of the NANOSMAT Society (FNS), a chartered physicist (CPhys), a chartered engineer (CEng), a chartered energy engineer, a registered professional engineer (R.P.E. in Electrical, Electronics, Energy), and a Senior Member of IEEE (SMIEEE). He serves on the editorial boards for several IEEE and SCI journals.

Abstract

P2Et is the standardized extract of Caesalpinia spinosa (C. spinosa), which has shown the ability to reduce primary tumors and metastasis in animal models of cancer. Although P2Et has been shown to be safe in healthy individuals, the biological activity and bioavailability can be increased by improving the dosage form. This study investigates the potential of P2Et encapsulation in a protein-based nanoparticles formulation aimed for oral administration of P2Et and its impact on treatment efficacy in a mouse model of breast cancer with orthotopically transplanted 4T1 cells. For this purpose, animals were treated with either free or encapsulated oral P2Et orally or i.p. and tumor growth and macrometastases were evaluated. All P2Et-based treatments significantly delayed tumor growth. The frequency of macrometastasis was reduced 1.1 times with P2Et i.p., while oral P2Et reduced it 3.2 times. The formulation containing nanoencapsulated P2Et was able to reduce the frequency of macrometastasis about 3.57 times. These results suggests that nanoencapsulation led to higher doses of effective P2Et being delivered, slightly improving bioavailability and biological activity. Therefore, the results of this study provides elements to consider P2Et as a potential adjuvant in the treatment of cancer, while the nanoencapsulation of P2Et provides a novel perspective on the delivery of these functional ingredients.

Biography

Ana Brotons-Canto has completed her PhD from the department of Pharmaceutical Technology and Chemistry at the University of Navarra (Spain). She is R&D manager at Nucaps Nanotechnology S.L.(Spain). The main focus of her research is to improve the oral bioavailability and/or stability of different compounds through encapsulation technologies. Se has participated in numerous conferences, fairs, and events. In addition se has take part of research projects at european and national level. In addition, as R&D manager at Nucaps, she has work in developments for third parties and in collaboration with the international companies. She collaborates with different journals as reviewer